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1.
Sensors (Basel) ; 22(23)2022 Nov 28.
Artigo em Inglês | MEDLINE | ID: mdl-36501965

RESUMO

In the traditional peripheral-security-early-warning system, the endpoint detection and pattern recognition of the signals generated by the distributed optical fiber vibration sensors is completed step-by-step and in an orderly manner. The method by which these two processes may be placed end-to-end in a network model and processed simultaneously to improve work efficiency has increasingly become the focus of research. In this paper, the target detection algorithm combines the endpoint-detection and pattern-recognition processes of the vibration signal, which can not only quickly locate the start and end vibration positions of the signal but also accurately identify a certain type of signal. You Only Look Once v4 (YOLOv4) is one of the most advanced target detection algorithms, achieving the optimal balance of speed and accuracy. To reduce the complexity of the YOLOv4 model and solve the dataset's unbalanced sample classification problem, we use a deep separable convolution (DSC) network and a focal loss function to improve the YOLOv4 model. In this paper, the five kinds of signals collected in real-time are visualized as two different datasets in oscillograph and time-frequency diagrams as detection objects. According to the experimental results, we obtained 98.50% and 93.48% mean Average Precision (mAP) and 84.8 and 69.9 frames per second (FPS), respectively, which are improved compared to YOLOv4. Comparing the improved algorithm with other optical fiber vibration signal recognition algorithms, the mAP and FPS values were improved, and the detection speed was about 20 times faster than that of other algorithms. The improved algorithm in this paper can quickly and accurately identify the vibration signal of external intrusion, reduce the false-alarm rate of the early-warning system, and improve the real-time detection rate of the system while ensuring high recognition accuracy.


Assuntos
Fibras Ópticas , Vibração , Modalidades de Fisioterapia , Oscilometria , Algoritmos
2.
Sensors (Basel) ; 22(16)2022 Aug 12.
Artigo em Inglês | MEDLINE | ID: mdl-36015773

RESUMO

Because of the problem of low recognition accuracy in the recognition of intrusion vibration events by the distributed Sagnac type optical fiber sensing system, this paper combines the traditional optical fiber vibration signal recognition idea and the characteristics of automatic feature extraction by a convolutional neural network (CNN) to construct a new endpoint detection algorithm and a method of fusing multiple-scale features CNN to recognize fiber vibration signals. Firstly, a new endpoint detection algorithm combining spectral centroid and energy spectral entropy product is used to detect the vibration part of the original signal, which is used to improve the detection effect of endpoint detection. Then, CNNs of different scales are used to extract the multi-level and multi-scale features of the signal. Aiming at the problem of information loss in the pooling process, a new method of combining differential pooling features is used. Finally, a multi-layer perceptron (MLP) is used to recognize the extracted features. Experiments show that the method has an average recognition accuracy rate of 98.75% for the four types of vibration signals. Compared with traditional EMD and VMD pattern recognition and 1D-CNN methods, the accuracy of the optical fiber vibration signal recognition is higher.


Assuntos
Fibras Ópticas , Vibração , Algoritmos , Redes Neurais de Computação
3.
PLoS One ; 15(11): e0242535, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33201919

RESUMO

A newly emerged coronavirus (COVID-19) seriously threatens human life and health worldwide. In coping and fighting against COVID-19, the most critical step is to effectively screen and diagnose infected patients. Among them, chest X-ray imaging technology is a valuable imaging diagnosis method. The use of computer-aided diagnosis to screen X-ray images of COVID-19 cases can provide experts with auxiliary diagnosis suggestions, which can reduce the burden of experts to a certain extent. In this study, we first used conventional transfer learning methods, using five pre-trained deep learning models, which the Xception model showed a relatively ideal effect, and the diagnostic accuracy reached 96.75%. In order to further improve the diagnostic accuracy, we propose an efficient diagnostic method that uses a combination of deep features and machine learning classification. It implements an end-to-end diagnostic model. The proposed method was tested on two datasets and performed exceptionally well on both of them. We first evaluated the model on 1102 chest X-ray images. The experimental results show that the diagnostic accuracy of Xception + SVM is as high as 99.33%. Compared with the baseline Xception model, the diagnostic accuracy is improved by 2.58%. The sensitivity, specificity and AUC of this model reached 99.27%, 99.38% and 99.32%, respectively. To further illustrate the robustness of our method, we also tested our proposed model on another dataset. Finally also achieved good results. Compared with related research, our proposed method has higher classification accuracy and efficient diagnostic performance. Overall, the proposed method substantially advances the current radiology based methodology, it can be very helpful tool for clinical practitioners and radiologists to aid them in diagnosis and follow-up of COVID-19 cases.


Assuntos
Infecções por Coronavirus/diagnóstico por imagem , Aprendizado Profundo , Pneumonia Viral/diagnóstico por imagem , Interpretação de Imagem Radiográfica Assistida por Computador/métodos , Tomografia Computadorizada por Raios X , Betacoronavirus , COVID-19 , Humanos , Pandemias , SARS-CoV-2 , Tórax/patologia , Tórax/ultraestrutura
4.
Appl Spectrosc ; 74(6): 674-683, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32031008

RESUMO

This study aimed to screen for thyroid dysfunction using Raman spectroscopy combined with an improved support vector machine (SVM). In spectral analysis, in order to further improve the classification accuracy of the SVM algorithm model, a genetic particle swarm optimization algorithm based on partial least squares is proposed to optimize support vector machine (PLS-GAPSO-SVM). In order to evaluate the performance of the algorithm, five optimization algorithms are used: grid search-based SVM (Grid-SVM), particle swarm optimization algorithm-based SVM (PSO-SVM), genetic algorithm-based SVM (GA-SVM), artificial fish coupled uniform design algorithm-based SVM (AFUD-SVM), and simulated annealing particle swarm optimization algorithm-based SVM (SAPSO-SVM). In this experiment, serum samples from 95 patients with confirmed thyroid dysfunction and 90 serum samples from normal thyroid function were used for Raman spectroscopy. The experimental results show that the GAPSO-SVM algorithm has a high average diagnostic accuracy of 95.08% and has high sensitivity and specificity (91.67%, 97.96%). Compared with the traditional optimization algorithm, the algorithm has high diagnostic accuracy, short execution time, and good reliability. It can be seen that Raman spectroscopy combined with GAPSO-SVM diagnostic algorithm has enormous potential in noninvasive screening of thyroid dysfunction.


Assuntos
Análise Espectral Raman , Máquina de Vetores de Suporte , Doenças da Glândula Tireoide/diagnóstico , Glândula Tireoide/ultraestrutura , Adulto , Idoso , Idoso de 80 Anos ou mais , Humanos , Programas de Rastreamento , Pessoa de Meia-Idade , Glândula Tireoide/patologia , Adulto Jovem
5.
J Biophotonics ; 13(2): e201900099, 2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-31593625

RESUMO

The spectral fusion by Raman spectroscopy and Fourier infrared spectroscopy combined with pattern recognition algorithms is utilized to diagnose thyroid dysfunction serum, and finds the spectral segment with the highest sensitivity to further advance diagnosis speed. Compared with the single infrared spectroscopy or Raman spectroscopy, the proposal can improve the detection accuracy, and can obtain more spectral features, indicating greater differences between thyroid dysfunction and normal serum samples. For discriminating different samples, principal component analysis (PCA) was first used for feature extraction to reduce the dimension of high-dimension spectral data and spectral fusion. Then, support vector machine (SVM), back propagation neural network, extreme learning machine and learning vector quantization algorithms were employed to establish the discriminant diagnostic models. The accuracy of spectral fusion of the best analytical model PCA-SVM, single Raman spectral accuracy and single infrared spectral accuracy is 83.48%, 78.26% and 80%, respectively. The accuracy of spectral fusion is higher than the accuracy of single spectrum in five classifiers. And the diagnostic accuracy of spectral fusion in the range of 2000 to 2500 cm-1 is 81.74%, which greatly improves the sample measure speed and data analysis speed than analysis of full spectra. The results from our study demonstrate that the serum spectral fusion technique combined with multivariate statistical methods have great potential for the screening of thyroid dysfunction.


Assuntos
Máquina de Vetores de Suporte , Glândula Tireoide , Algoritmos , Análise de Componente Principal , Análise Espectral Raman , Tecnologia
6.
Spectrochim Acta A Mol Biomol Spectrosc ; 215: 244-248, 2019 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-30831394

RESUMO

This study presents a rapid and non-invasive method to screen high renin hypertension using serum Raman spectroscopy combined with different classification algorithms. The serum samples taken from 24 high renin hypertension patients and 22 non-high renin hypertension samples were measured in this experiment. Tentative assignments of the Raman peaks in the measured serum spectra suggested specific biomolecular changes between the groups. Principal component analysis (PCA) was first used for feature extraction and reduced the dimension of high-dimension spectral data. Then, support vector machine (SVM), linear discriminant analysis (LDA) and k-nearest neighbor (KNN) algorithms were employed to establish the discriminant diagnostic models. The accuracies of 93.5%, 93.5% and 89.1% were obtained from PCA-SVM, PCA-LDA and PCA-KNN models, respectively. The results from our study demonstrate that the serum Raman spectroscopy technique combined with multivariate statistical methods have great potential for the screening of high renin hypertension. This technique could be used to develop a portable, rapid, and non-invasive device for screening high renin hypertension.


Assuntos
Hipertensão/diagnóstico , Renina/sangue , Análise Espectral Raman/métodos , Algoritmos , Diagnóstico por Computador , Análise Discriminante , Humanos , Hipertensão/sangue , Máquina de Vetores de Suporte
7.
Opt Express ; 23(19): 24626-33, 2015 Sep 21.
Artigo em Inglês | MEDLINE | ID: mdl-26406664

RESUMO

This paper proposes a label-free and spectrometer-free method for biological detection with high detecting resolution. Taking advantage of the optical properties of porous silicon microcavity, the refractive index changes caused by biological reaction can be detected by measuring the incident angle of the minimum reflected light intensity. Based on the above method, label-free eight-base pair DNA detection can be realized with a corresponding detection limit is as low as 87 nM. This method provides high detecting resolution at a low equipment cost, and can be further used to develop an advanced instrument for biological detection.

8.
Biosens Bioelectron ; 39(1): 329-33, 2013 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-22921092

RESUMO

A fabrication of a novel simple porous silicon polybasic photonic crystal with symmetrical structure has been reported as a nucleic acid biosensor for detecting antifreeze protein gene in insects (Microdera puntipennis dzhungarica), which would be helpful in the development of some new transgenic plants with tolerance of freezing stress. Compared to various porous silicon-based photonic configurations, porous silicon polytype layered structure is quite easy to prepare and shows more stability; moreover, polybasic photonic crystals with symmetrical structure exhibit interesting optical properties with a sharp resonance in the reflectance spectrum, giving a higher Q factor which causes higher sensitivity for sensing performance. In this experiment, DNA oligonucleotides were immobilized into the porous silicon pores using a standard crosslink chemistry method. The porous silicon polybasic symmetrical structure sensor possesses high specificity in performing controlled experiments with non-complementary DNA. The detection limit was found to be 21.3nM for DNA oligonucleotides. The fabricated multilayered porous silicon-based DNA biosensor has potential commercial applications in clinical chemistry for determination of an antifreeze protein gene or other genes.


Assuntos
Proteínas Anticongelantes/genética , DNA/análise , Proteínas de Insetos/genética , Insetos/genética , Hibridização de Ácido Nucleico/métodos , Silício/química , Animais , Técnicas Biossensoriais/métodos , DNA/genética , Genes de Insetos , Limite de Detecção , Porosidade , Refratometria
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